Bitter melon (Ampalaya) has been traditionally used for numerous health problems such as, high blood pressure, skin infections, painful menstruation, kidney stones, colic, malaria, glaucoma, high cholesterol, diarrhea, stomach cramps, hemorrhoids, and fever.
Bitter melon was composed of alkaloids, glycoside, peptides, acids, cucurbitins, charantin, cucurbitacins, momordine, momorcharins, and proteins.
It is assumed that the main components responsible for the hypoglycemic properties are charantin, cucurbutanoids, momordicin, and oleanolic acids.
A current scientific finding has shown that bitter melon contains hypoglycemic and anticancer effects.
The researchers that came from the Garvan Institute of Medical Research and the Shanghai Institute of Materia Medica have revealed the effectiveness of treating Type 2 diabetes with the help of bitter melon.
Bitter melon contains particular chemical mixtures that activate AMPK, which encourages the movement of glucose transporters to the surface of the cell. “More transporters on cells’ surfaces upsurge the acceptance of glucose from the circulation in the blood into the tissues of the body, which includes muscles, therefore, pulling down the blood sugar levels.”
In the Journal of Ethno pharmacology, researches have decided that, “Bitter melon contains an unassertive hypoglycemic effect and it meaningfully lessened fructoisamine levels from the starting point between patients with Type 2 diabetes who received 2,000 mg/day. Nevertheless, the hypoglycemic effect that the bitter melon has was lesser than the metformin at 1,000 mg/day.”
BITTERMELON ON BREAST CANCER
The extract that came from the bitter melon, is a usual dietary supplement, which exerts a meaningful effect against the growth of the breast cancer cells and it may eventually become a chemo preventive agent against this type of cancer, according to the result of a recent study.
Bitter melon extract has been nurtured in Asia, Africa, as well as South America. The extract of this vegetable is being promoted as a dietary supplement in Western Countries, since it is widely known to have added glycosides including momordine, Vitamin C, carotenoids, flavonoids, and polyphenols.
A recent study that was conducted by Saint Louis University scientists have discovered that the extract of bitter melon activates a chain of events on a cellular level that hinders breast cancer cells from reproducing, and it eventually kills them. “The extract that came from the bitter melon moderates numerous signal transduction pathways, which encourages the death of the breast cancer cells. This extract can be used as a dietary supplement for the stoppage of breast cancer”, according to the head researcher.
Bitter melon can be consumed as a fruit, it can be transform as a drink, or it can be added to your smoothies. The extract from the bitter melon is also available as an herbal supplement.